Fed up with her parents’ bickering, poor-little-rich-girl Maya (Dylan Penn) moves in with her boyfriend who is squatting in an old, condemned building on Manhattan’s Lower East Side. With neighbors that are meth heads, junkies and degenerates, this depraved hell hole is even more toxic than it appears: After a virus born from their combined noxious waste and garbage infects the building’s residents, one by one, they succumb to a terrifying pathogen that turns them into bloodthirsty, rampaging killers and transforms their building into a savage slaughterhouse.
Abe is a man who is in his thirties and who lives with his parents. He works regretfully for his father while pursuing his hobby of collecting toys. Aware that his family doesn’t think highly of him, he tries to spark a relationship with Miranda, who recently moved back home after a failed literary/academic career. Miranda agrees to marry Abe out of desperation, but things go awry.