After a dying Voodoo queen chooses an adopted apprentice as her successor, her true heir is outraged. Seeking revenge, he buys the bones of Blacula the vampire off of a dealer, and uses voodoo to bring the vampire back to do his bidding. In turn, Blacula turns him into a vampire and makes him his slave. Meanwhile, a police officer with a large collection of African antiques and an interest in the occult investigates the murders caused by Blacula and his vampire horde.
A frustrated pianist himself, music journalist Myles Clarkson is thrilled to interview virtuoso Duncan Ely. Duncan, however, is terminally ill and not much interested in Myles until noticing that Myles’ hands are ideally suited for piano. Suddenly, he can’t get enough of his new friend, and Myles’ wife, Paula, becomes suspicious of Duncan’s intentions. Her suspicions grow when Duncan dies and Myles mysteriously becomes a virtuoso overnight.