The only business in the Wild West town of Jericho that corrupt sheriff Alex Flood doesn’t control behind the scenes is the stagecoach owned by tough-willed widow Molly Lang and her right-hand man, Hickman. Former marshal Dolan, recently hired by Lang and Hickman as a driver, wants to stay out of the mess, but when he sees Flood’s henchman Yarbrough assault Lang, he steps up to fight the corruption.
A group of unlikely travelling companions find themselves on the same stagecoach to Cheyenne. They include a drunken doctor, a bar girl who’s been thrown out of town, a professional gambler, a travelling liquor salesman, a banker who has decided to embezzle money, a gun-slinger out for revenge and a young woman going to join her army captain husband. All have secrets but when they are set upon by an Indian war party and then a family of outlaws, they find they must all work together if they are to stay alive.